In this less-stable global environment, there is also the prospect of space weapons causing less stable regional environments. That leads into my second point: space weapons will also cause regional instabilities. Integrating space weapons into military operations will undoubtedly have serious consequences for the progression of conflict situations. In
most war games that include space assets, commanders have repeatedly discovered that pre-emptively destroying or denying an opponent's space-based assets, using space weapons to do so, is both appealing and often, inevitably, leads to rapid escalation in a full-scale war, even triggering nuclear responses.

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Deblois, Bruce M. "Weapons in Space." Carnegie International Non-Proliferation Conference. Ed. . Washington, D.C.: Council on Foreign Relations, . [ 3 quotes ]